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CAS RN: 329003-65-8 | 产品编码: M2289
Monosodium Risedronate Hemipentahydrate
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| 产品编码 | M2289 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__7H__1__0NNaO__7P__2·2^^1/__2H__2O = 350.13 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片）, 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 329003-65-8 |
| 相关CAS RN | 115436-72-1&105462-24-6 |
| Reaxys-RN | 6361090 |
| PubChem物质ID | 135727372 |
| Merck Index (14) | 8232 |
| MDL编号 | MFCD01706268 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Water | 11.9 to 13.9 % |
物性（参考值）
| 水溶性 | 可溶 |
| 溶解性（不溶于） | 乙醇 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P260 : Do not breathe dusts or mists. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相关法规
| RTECS# | SZ8567500 |
运输信息
| HS编码* | 2933.39-000 |
应用
Pharmacology Studies
References
- Bisphosphonates Inhibit the Growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A Potential Route to Chemotherapy
- Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system
- Application of on-line Raman spectroscopy for characterizing relationships between drug hydration state and tablet physical stability
应用
Bone Resorption Inhibitors
Reference
- 1)Anti-bone resorption
- a)J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers., J. Pharmacol. Exp. Ther. 2001, 296, 235.
- b)E. Hiroi-Furuya, T. Kameda, K. Hiura, H. Mano, K. Miyazawa, Y. Nakamaru, M. Watanabe-Mano, N. Okuda, J. Shimada, Y. Yamamoto, Y. Hakeda, M. Kumegawa, Calcif. Tissue Int. 1999, 64, 219.
参考文献
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