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CAS RN: 602-85-7 | 产品编码: L0413
Lysergol
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纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 麦角醇
- (8β)-9,10-二脱氢-6-甲基麦角灵-8-甲醇
- [(6aR,9R)-7-甲基-4,6,6a,7,8,9-六氢吲哚并[4,3-fg]喹啉-9-基]甲醇
- (8β)-9,10-Didehydro-6-methylergoline-8-methanol
- [(6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl]methanol
产品文档：
| 产品编码 | L0413 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__6H__1__8N__2O = 254.33 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,加热 |
| CAS RN | 602-85-7 |
| Reaxys-RN | 88476 |
| MDL编号 | MFCD00010029 |
技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation | +50.0 to +55.0 deg (C=0.18, pyridine) |
| NMR | confirm to structure |
物性（参考值）
GHS
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| 信号词 | Danger |
| 危险性说明 | H300 : Fatal if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | KE6330000 |
运输信息
| UN编号 | UN1544 |
| 类别 | 6.1 |
| 包装类别 | II |
| HS编码* | 2939.69-000 |
应用
Lysergol: A Pharmacologically Important Ergot Alkaloid
Lysergol is belong to the ergot alkaloids that are pharmacologically important indole alkaloids which are secondary metabolites produced by filamentous fungi such as Claviceps purpurea.1) Lysergol has important pharmacological properties that engage various serotonin G protein-coupled receptors such as serotonin 5-HT1A and 5-HT2 receptors.2,3) In addition, lysergol is a natural bio-enhancer which promote and augment the bioavailability of the pharmaceutical agents.4-6) (The product is for research purpose only.)
References
- 1) Biochemistry of Ergot Alkaloids—Achievements and Challenges
- 2) Ergolines as selective 5-HT1 agonists
- 3) Cycloalkanecarboxylic Esters Derived from Lysergol, Dihydrolysergol-I, and Elymoclavine as Partial Agonists and Antagonists at Rat 5-HT2A Receptors: Pharmacological Evidence that the Indolo[4,3-fg]quinoline System of the Ergolines Is Responsible for High 5-HT2A Receptor Affinity
- 4) A mechanistic investigation of the bioavailability enhancing potential of lysergol, a novel bioenhancer, using curcumin
- 5) Simultaneous quantification of berberine and lysergol by HPLC-UV: evidence that lysergol enhances the oral bioavailability of berberine in rats
- 6) Natural bioenhancers: an overview
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技术规格
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