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CAS RN: 66108-95-0 | 产品编码: I0903
Iohexol (mixture of isomers)
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纯度/分析方法: >98.0%(HPLC)(N)
别名：
- 碘海醇 (异构体混合物)
- N,N'-双(2,3-二羟基丙基)-5-[N-(2,3-二羟基丙基)乙酰氨基]-2,4,6-三碘异酞酰胺 (异构体混合物)
- 5-[乙酰基(2,3-二羟基丙基)胺]-N,N'-双(2,3-二羟基丙基)-2,4,6-三碘异酞酰胺 (异构体混合物)
- N,N'-Bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide (mixture of isomers)
- 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (mixture of isomers)
产品文档：
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 % (total of isomers) |
| Purity(with Total Nitrogen) | min. 98.0 % |
物性（参考值）
| 熔点 | 180 °C |
| 最大吸收波长 | 245 nm (H__2O) |
| 水溶性 | 可溶 |
GHS
相关法规
| RTECS# | CZ2205000 |
运输信息
| HS编码* | 2924.29-000 |
应用
Iohexol: A Water-Soluble Nonionic Radiographic Contrast Agent
Iohexol is a water-soluble nonionic contrast agent of low osmolality, commonly used in diagnostic radiography of the brain and spinal cord. Iohexol is also used for a marker for glomerular filtration rate (GFR): after intravenous injection, it is quantitatively recovered in the urine; the elimination occurs by glomerular filtration. It is called iohexol clearance test and used in a standard test of kidney function. For your reference, [A2169] is a key synthetic intermediate of it. (The product is for research purpose only.)
References
- Chemotoxicity of contrast media and clinical adverse effects: a review
- Iohexol: a review of its pharmacological properties and use as a contrast medium in myelography and neuroangiography
- Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate
- Evaluation of a single injection method, using iohexol, for estimating glomerular filtration rate in cats and dogs
- S. A. Brown, D. R. Finco, D. Boudinot, J. Wright, S. L. Tarver, T. Cooper, Am. J. Vet. Res. 1996, 57, 105.
- In Vivo Performance of a Liposomal Vascular Contrast Agent for CT and MR-Based Image Guidance Applications
参考文献
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