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CAS RN: 489-32-7 | 产品编码: I0862
Icariin
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| 产品编码 | I0862 |
| 纯度/分析方法 | >96.0%(HPLC) |
| 分子式/分子量 | C__3__3H__4__0O__1__5 = 676.67 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片）, 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 489-32-7 |
| Reaxys-RN | 76280 |
| PubChem物质ID | 253659823 |
| Merck Index (14) | 3617 |
| MDL编号 | MFCD00210516 |
技术规格
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Specific rotation [a]20/D | -83.0 to -90.0 deg(C=1,Pyridine) |
物性（参考值）
| 熔点 | 237 °C |
| 比旋光度 [α]D | -84° (C=1,Pyridine) |
| 最大吸收波长 | 350(MeOH) nm |
GHS
相关法规
| RTECS# | DJ2980500 |
运输信息
| HS编码* | 2938.90-000 |
应用
Bone research
References
- Icariin: A Potential Osteoinductive Compound for Bone Tissue Engineering
- Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells
- Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells
- Icariin inhibits the osteoclast formation induced by RANKL and macrophage-colony stimulating factor in mouse bone marrow culture
应用
Icariin: The Major Bioactive Component in Herba Epimedii
Icariin, a type of flavonoid, is the major bioactive component in Herba Epimedii which has been historically used in combination with other herbs to treat skeletal diseases in traditional Chinese medicine (TCM). It has been reported that icariin shows various pharmacological effects such as osteoprotective effect, antioxidative effect, osteoprotective effect, neuroprotective effect, cardiovascular protective effect, anti-cancer effect, anti-inflammation effect, immunoprotective effect and reproductive function. (The product is for research purpose only.)
References
- Herba Epimedii: anti-oxidative properties and its medical implications (a review)
- Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling (a review)
- Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii (a review)
参考文献
文章/手册
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