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CAS RN: 54-42-2 | 产品编码: I0258
5-Iodo-2'-deoxyuridine
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This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| 产品编码 | I0258 |
| 纯度/分析方法 | >99.0%(T) |
| 分子式/分子量 | C__9H__1__1IN__2O__5 = 354.10 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 光,空气 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 54-42-2 |
| Reaxys-RN | 30397 |
| PubChem物质ID | 87571623 |
| SDBS (AIST Spectral DB) | 4820 |
| Merck Index (14) | 4891 |
| MDL编号 | MFCD00134656 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Specific rotation [a]20/D | +28.0 to +31.0 deg(C=1, 1mol/L NaOH sol.) |
| Solubility in hot Water | almost transparency |
物性（参考值）
| 比旋光度 [α]D | 30° (C=1,1mol/L NaOH sol.) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. H341 : Suspected of causing genetic defects. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P405 : Store locked up. |
相关法规
| RTECS# | YU7700000 |
运输信息
| HS编码* | 2934.99-000 |
应用
Idoxuridine: A Thymidine Analog and an Antiviral Agent against Herpes Simplex Virus (HSV)
Idoxuridine is a thymidine analog that is used as an antiviral agent against herpes simplex virus (HSV). Idoxuridine has a chemical structure similar to thymidine, except that the 5-methyl group is replaced by iodine. Herpes simplex virus utilizes thymidine in the synthesis of deoxyribonucleic acid (DNA). When idoxuridine is substituted for thymidine in the viral DNA, the viral is unable to replicate its DNA. (The product is for research purpose only.)
References
- Synthesis and biological activities of iododeoxyuridine, an analog of thymidine
- The effects of incorporation of 5-halogenated deoxyuridines into the DNA of eukaryotic cells (a review)
- Specific targets for antiviral drugs (a review)
参考文献
文章/手册
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