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CAS RN: 161798-01-2 | 产品编码: E1394
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
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技术规格
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 113.0 to 117.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 116 °C |
GHS
相关法规
运输信息
| HS编码* | 2934.99-000 |
应用
A Synthetic Intermediate of Febuxostat and Its Related Compounds
E1394 (this product) and [E1049] are used as synthetic intermediates of febuxostat [F0847], which is a non-purine-selective xanthine oxidase inhibitor, and its related compounds.
References
- Process for the preparation of 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylicacid (febuxostat)
- Synthesis of the Major Metabolites of Febuxostat
- Ultra-high performance liquid chromatographic determination of genotoxic impurities in febuxostat drug substance and products
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技术规格
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