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CAS RN: 58-28-6 | 产品编码: D6181
Desipramine Hydrochloride
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纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 盐酸地昔帕明
- 3-(10,11-二氢-5H-二苯并[b,f]氮杂卓-5-基)-N-甲基-1-丙胺盐酸盐
- 3-(10,11-二氢-5H-二苯并[b,f]氮杂卓-5-基)-N-甲基丙烷-1-胺盐酸盐
- 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methyl-1-propanamine Hydrochloride
- 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine Hydrochloride
产品文档：
| 产品编码 | D6181 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__8H__2__2N__2·HCl = 302.85 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,湿气 (吸湿) |
| CAS RN | 58-28-6 |
| Reaxys-RN | 4166006 |
| MDL编号 | MFCD00058108 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 212.0 to 216.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 214 °C |
| 最大吸收波长 | 250(H2O) nm |
| 水溶性 | 可溶 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H336 : May cause drowsiness or dizziness. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相关法规
| RTECS# | HO0525000 |
运输信息
| HS编码* | 2933.99-000 |
应用
Desipramine hydrochloride: An Active Tricyclic Antidepressant
Desipramine hydrochloride, a metabolite of imipramine [I0971], is an active tricyclic antidepressant. While the precise mechanism of action of tricyclic antidepressants is unknown, many studies suggest that they restore normal levels of neurotransmitters, such as norepinephrine and serotonin, by blocking the reuptake of these substances from the synapse in the central nervous system. (The product is for research purpose only.)
References
- Clinical Pharmacokinetics of Imipramine and Desipramine
- Studies on the distinction between uptake inhibition and release of [3H] dopamine in rat brain tissue slices
- The tail suspension test: a new method for screening antidepressants in mice
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技术规格
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