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CAS RN: 522-17-8 | 产品编码: D5646
(-)-Deguelin
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技术规格
| Appearance | White to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | -59.0 to -63.0 deg(C=1, methanol) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 87 °C |
| 最大吸收波长 | 314(MeOH) nm |
GHS
相关法规
| RTECS# | DX1500000 |
运输信息
| HS编码* | 2932.99-000 |
应用
Deguelin: a naturally occurring rotenoid and an Akt inhibitor
Deguelin is a naturally occurring rotenoid of the flavonoid family contained in several plant species belonging to the legume family such as Derris trifoliata Lour, and has been used as a naturally occurring insecticide. In vitro and in vivo studies suggests that deguelin exerts potent anticancer activity against multiple cancer types and exhibits chemopreventive potential in Akt-inducible transgenic mouse models. (The product is for research purpose only.)
References
- Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid
- Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis
- Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential (a review)
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技术规格
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