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CAS RN: 19130-96-2 | 产品编码: D5612
1-Deoxynojirimycin
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| 产品编码 | D5612 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__6H__1__3NO__4 = 163.17 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气 |
| 包装和容器 | 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 19130-96-2 |
| Reaxys-RN | 1524395 |
| PubChem物质ID | 468591452 |
| Merck Index (14) | 2905 |
| MDL编号 | MFCD00063474 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Melting point | 201.0 to 205.0 °C |
| Specific rotation | +44.0 to +48.0 deg(C=1, water) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 203 °C |
GHS
相关法规
| RTECS# | TN4350300 |
运输信息
| HS编码* | 2933.39-000 |
应用
1-Deoxynojirimycin: An α-Glucosidase Inhibitor
1-Deoxynojirimycin, an alkaloid azasugar, is a bioactive compound that exists in mulberry leaves and Commelina communis (dayflower) as well as from several bacterial strains. It has been reported that 1-deoxynojirimycin has diverse pharmacological properties as an α-glucosidase inhibitor, such as antihyperglycemic, anti-obesity, and antiviral activities.1,2) Furthermore, 1-deoxynojirimycin and its N-alkylated derivative (miglitol [M2302]: N-butyldeoxynojirimycin) have been used as α-glucosidase inhibitors that smooth post-prandial peak plasma glucose levels and thus improve glycemic control.3) (The product is for research purpose only.)
References
- 1) 1-deoxynojirimycin: occurrence, extraction, chemistry, oral pharmacokinetics, biological activities and in silico target fishing (a review)
- 2) Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions
- 3) N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis
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