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CAS RN: 630423-36-8 | 产品编码: D5182
1,7-Dichloro-4-methoxyisoquinoline
技术规格
Appearance | White to Yellow to Orange powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 137.0 to 142.0 °C |
NMR | confirm to structure |
物性(参考值)
熔点 | 139 °C |
GHS
象形图 | |
信号词 | Warning |
危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
HS编码* | 2933.49-000 |
应用
A Synthetic Intermediate of Non-Structural Protein 3 (NS3) Serine Protease Inhibitors
This product is used for the synthesis of non-structural protein 3 (NS3) serine protease inhibitors for the treatment of Hepatitis C Virus Infection, such as asunaprevir (BMS-650032).
References
- The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
- Development of a Control Strategy for a Final Intermediate to Enable Impurities Control
参考文献
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