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Published TCIMAIL newest issue No.197 | Notice of Discontinuing the Use of Password-Protected Compressed Files | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
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CAS RN: 14484-47-0 | 产品编码: D4523
产品编码 | D4523 |
纯度/分析方法 | >98.0%(HPLC)(N) |
分子式/分子量 | C__2__5H__3__1NO__6 = 441.52 |
外观与形状(20°C) | 固体 |
储存温度 | 冷藏 (0-10°C) |
应避免的情况 | 加热 |
包装和容器 | 1G-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 14484-47-0 |
Reaxys-RN | 4947650 |
PubChem物质ID | 253661789 |
Merck Index (14) | 2862 |
MDL编号 | MFCD00866106 |
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(with Total Nitrogen) | min. 98.0 % |
Melting point | 256.0 to 260.0 °C |
Specific rotation [a]20/D | +63.0 to +74.0 deg(C=0.5, CHCl3) |
物性(参考值)
熔点 | 258 °C |
比旋光度 [α]D | 73° (C=0.5,CHCl3) |
溶解性(可溶于) | 二氯甲烷 |
GHS
相关法规
RTECS# | TU4157050 |
运输信息
HS编码* | 2937.29-000 |
应用
Deflazacort: A Synthetic Glucocorticoid with Anti-Inflammatory and Immunosuppressive Activity
Deflazacort is a synthetic glucocorticoid and an oxazoline derivative of prednisolone [P0637] with anti-inflammatory and immunosuppressive activity. Deflazacort is an ester prodrug and metabolized to form the active metabolite 21-desacetyldeflazacort.
References
- Deflazacort. A review of its pharmacological properties and therapeutic efficacy
- Disposition of a new steroidal anti-inflammatory agent, deflazacort, in rat, dog and man
- Deflazacort: a glucocorticoid with few metabolic adverse effects but important immunosuppressive activity
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