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CAS RN: 106266-04-0 | 产品编码: D3979
4-(2,4-Difluorobenzoyl)piperidine Hydrochloride
技术规格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(with Total Nitrogen) | min. 98.0 % |
物性(参考值)
水溶性 | 可溶 |
GHS
象形图 | |
信号词 | Warning |
危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
HS编码* | 2933.39-000 |
应用
A Synthetic Intermediate of Benzisoxazole Dopamine D2 and Serotonin Receptors Antagonists
This product has been used as a synthetic intermediate of benzisoxazole dopamine D2 and serotonin receptors antagonists, such as Iloperidone [I0926] and risperidone [R0087].
References
- Flow Synthesis in Hot Water: Synthesis of the Atypical Antipsychotic Iloperidone
- Improved process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl}-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone)
- l. Pongó, J. Reiter, G. Simig, G. Berecz, G. Clementis, P. Slégel, J. Szulágyi, L. Koncz, G. V. Donáth, K. Nagy, G. Körtvélyessy, WO2003042212 A1.
参考文献
TCIMail
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技术规格
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