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CAS RN: 66592-87-8 | 产品编码: C3951
Cefadroxil Monohydrate
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纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 头孢羟氨苄 一水合物
- (6R,7R)-7-[[(2R)-2-氨基-2-(4-羟基苯基)乙酰基]氨基]-3-甲基-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸 一水合物
- (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Monohydrate
产品文档：
| 规格 | 单价 | 同一天 | 2-3个工作日 | 数量 |
|---|---|---|---|---|
| 5G |
S$160.50
|
19 | 8 |
|
| 25G |
S$559.50
|
20 | 12 |
|
| 产品编码 | C3951 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__6H__1__7N__3O__5S·H__2O = 381.41 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,湿气 (吸湿) |
| CAS RN | 66592-87-8 |
| Reaxys-RN | 5694571 |
| MDL编号 | MFCD01682047 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Water | 4.0 to 6.0 % |
| Specific rotation | +165 to +178 deg(C=1,water)(calcd.on anh.substance) |
| NMR | confirm to structure |
物性（参考值）
| 水溶性 | 微溶 |
| 溶解性（不溶于） | 乙醇 |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2941.90-000 |
应用
Cefadroxil: A Semisynthetic Cephalosporin against a Wide Range of Gram-Positive and Gram-Negative Bacteria
Cefadroxil, a semisynthetic cephalosporin, is active against a wide range of Gram-positive and Gram-negative bacteria. It inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin-binding proteins (PBPs). The result is the formation of a defective, osmotically unstable cell wall and bacterial cell lysis (bactericidal effect). It is an oral cephalosporin similar in structure and spectrum of antibacterial activity to cephalexin [C2248] and cephradine [C2988], but with different pharmacokinetic properties. Not only does cefadroxil have a longer serum half-life, but it is virtually unaffected by concurrent food intake. (The product is for research purpose only.)
References
- Cefadroxil, a new broad-spectrum cephalosporin
- Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine
- Selective spectrophotometric determination of phenolic β-lactam antibiotics in pure forms and in their pharmaceutical formulations
- Characteristics, Properties and Analytical Methods of Cefadroxil: A Review
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