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Notice of Discontinuing the Use of Password-Protected Compressed Files | Product Document Searching Made Easy by 2D Code! | TCI Life Science News February 2025 | [Product Highlights] Chemiluminescent Reagents for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
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CAS RN: 184475-71-6 | 产品编码: C3647
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
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技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 293 °C |
GHS
相关法规
运输信息
| HS编码* | 2933.59-000 |
应用
A Key Synthetic Intermediate of Gefitinib
This product is a key synthetic intermediate of gefitinib (ZD1839) [G0546] which is a potent and selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
References
- Studies leading to the identification of ZD1839 (iressa): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer
- Improved synthesis of substituted 6,7-dihydroxy-4-quinazolineamines: tandutinib, erlotinib and gefitinib
- Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives
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技术规格
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