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CAS RN: 33818-15-4 | 产品编码: C3445
Cytidine 5'-Diphosphocholine Sodium Salt
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| 产品编码 | C3445 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__1__4H__2__5N__4NaO__1__1P__2 = 510.31 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (<0°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 湿气 (吸湿),加热 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 33818-15-4 |
| 相关CAS RN | 987-78-0 |
| Reaxys-RN | 4110040 |
| PubChem物质ID | 468591112 |
| MDL编号 | MFCD00037486 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 %(calcd.on anh.substance) |
| Water | max. 6.0 % |
物性（参考值）
| 熔点 | 250 °C(dec.) |
| 比旋光度 [α]D | 12.5° (C=1.0,H2O) |
| 最大吸收波长 | 280(HCl aq.) nm |
GHS
相关法规
运输信息
| HS编码* | 2934.99-000 |
应用
Citicoline: An Intermediate in the Biosynthesis of Cell Membrane Phospholipids Acting as a Neuroprotective Agent
Citicoline (cytidine 5'-diphosphocholine, CDP-choline) is an intermediate in the biosynthesis of cell membrane phospholipids. Therefore, citicoline can activate the biosynthesis of phospholipids in the neuronal membrane, increase cerebral metabolism and increase the level of various neurotransmitters, such as acetylcholine [A0084 (chloride)] and dopamine [A0305 (hydrochloride)]. Citicoline has shown beneficial effects in various central nervous system (CNS) injury models and neurodegenerative diseases, such as stroke, brain trauma, and Parkinson's disease. (The product is for research purpose only.)
References
- Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline (a review)
- Citicoline: neuroprotective mechanisms in cerebral ischemia
- Cytidine 5'-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
- Spectrophotometric determination of Citicoline sodium in pure form and pharmaceutical formulation
- Stability indicating LC method for the determination of citicoline sodium in injection formulation
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