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CAS RN: 2030-63-9 | 产品编码: C2866
Clofazimine
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| 产品编码 | C2866 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__2__7H__2__2Cl__2N__4 = 473.40 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 2030-63-9 |
| Reaxys-RN | 60420 |
| PubChem物质ID | 253661510 |
| Merck Index (14) | 2373 |
| MDL编号 | MFCD00056793 |
技术规格
| Appearance | Yellow to Amber to Dark red powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
物性（参考值）
| 熔点 | 219 °C |
| 水溶性 | 不溶 |
| 溶解性（可溶于） | 氯仿, 二甲基甲酰胺 |
| 溶解性（微溶于） | 乙醚, 丙酮 |
GHS
| 危险性说明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相关法规
| RTECS# | SG1578000 |
运输信息
| HS编码* | 2933.99-000 |
应用
Clofazimine: A Lipophilic Riminophenazine Antibiotic
Clofazimine, a lipophilic riminophenazine antimicrobial, possesses both antimycobacterial and anti-inflammatory activities， and used in the treatment of mycobacterial diseases including leprosy. The antibiotic properties of clofazimine are not fully described. However, clofazimine works by binding to the bacterial DNA, thereby inhibiting bacterial proliferation. (The product is for research purpose only.)
References
- The pharmacology, metabolism, and chemistry of clofazimine (a review)
- Antimycobacterial activities of riminophenazines (a review)
- Effective treatment of acute and chronic murine tuberculosis with liposome-encapsulated clofazimine
- Reduction of Clofazimine by Mycobacterial Type 2 NADH:Quinone Oxidoreductase: A Pathway for the Generation of Bactericidal Levels of Reactive Oxygen Species
- Clofazimine: current status and future prospects (a review)
参考文献
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