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CAS RN: 23325-78-2 | 产品编码: C2248
Cephalexin Monohydrate
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补充产品信息:
This product has not been tested for potency and is guaranteed for chemical purity.
技术规格
Appearance | White to Orange to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 97.0 % |
Specific rotation [a]20/D | +149 to +158 deg(C=0.5, H2O)(calcd.on anh.substance) |
Water | 4.0 to 8.0 % |
物性(参考值)
比旋光度 [α]D | 154° (C=0.5,H2O) |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H317 : May cause an allergic skin reaction. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
RTECS# | XI0350000 |
运输信息
HS编码* | 2941.90-000 |
应用
Cephalexin: The Most Popular First-Generation Semisynthetic Cephalosporin Antibiotic
Cephalexin is the most popular first-generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminodesacetoxycephalosporanic acid (7-ADCA) [A2075]. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. The side chain substituents on the cephalosporin nucleus are the same as the substituents on the penicillin nucleus of ampicillin [A2092]. Cephalexin attains much higher serum concentrations than ampicillin in equivalent oral doses and is much less bound to serum proteins than cephalothin [C2769].
References
- Cephalexin. A review of its antibacterial, pharmacological and therapeutic properties
- Review of the spectrum and potency of orally administered cephalosporins and amoxicillin/clavulanate
参考文献
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