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CAS RN: 635-65-4 | 产品编码: B0460
Bilirubin
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| 产品编码 | B0460 |
| 纯度/分析方法 | >80.0%(HPLC) |
| 分子式/分子量 | C__3__3H__3__6N__4O__6 = 584.67 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 光,空气,加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片）, 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 635-65-4 |
| PubChem物质ID | 87563495 |
| SDBS (AIST Spectral DB) | 5074 |
| Merck Index (14) | 1218 |
| MDL编号 | MFCD00005499 |
技术规格
| Appearance | Orange to Brown powder to crystal |
| Purity(HPLC) | min. 80.0 area% |
| Lambda max. | 450.0 to 454.0 nm(CHCl3) |
| Molar extinction coefficient | 56,000 to 61,000(CHCl3, 450.0 to 454.0 nm) |
| NMR | confirm to structure |
物性（参考值）
| 最大吸收波长 | 452(CHCl3) nm |
GHS
相关法规
| RTECS# | DU3038000 |
运输信息
| HS编码* | 2933.79-000 |
应用
Bilirubin: The End Product of Heme Catabolism with Interesting Biochemical and Biological Properties
Bilirubin, the principal bile pigment, is the end product of heme catabolism, formed when heme is cleaved by heme oxygenase-1 (HO-1). HO-1 catabolizes heme into three products: biliverdin (which is rapidly converted to bilirubin by biliverdin reductase), carbon monoxide (CO) and free iron ion (Fe3+). For many years, bilirubin was thought as a waste product with no physiological function. But recently, HO-1 has been recognized to have immunomodulatory, antioxidant and anti-inflammatory properties.1,2) And then, bilirubin has also been recognized to have a number of new and interesting biochemical and biological properties.3,4) (The product is for research purpose only.)
References
- 1) Heme oxygenase-1: unleashing the protective properties of heme (a review)
- 2) Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications (a review)
- 3) Bilirubin: An endogenous product of heme degradation with both cytotoxic and cytoprotective properties (a review)
- 4) Bilirubin chemistry and metabolism; harmful and protective aspects (a review)
参考文献
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