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CAS RN: 39524-08-8 | 产品编码: A3635
Asperosaponin VI
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纯度/分析方法: >95.0%(HPLC)
别名：
- 川续断皂苷VI
- 类叶牡丹苷A
- 1-O-[3β-(α-L-吡喃阿拉伯糖氧基)-23-羟基-28-氧代齐墩果-12-烯-28-基]-6-O-β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷
- Leiyemudanoside A
- 1-O-[3β-(α-L-Arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-β-D-glucopyranosyl-β-D-glucopyranose
产品文档：
| 产品编码 | A3635 |
| 纯度/分析方法 | >95.0%(HPLC) |
| 分子式/分子量 | C__4__7H__7__6O__1__8 = 929.11 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (-20°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 39524-08-8 |
| Reaxys-RN | 5224820 |
| MDL编号 | MFCD25371916 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | +15.0 ～ +19.0 deg(C=1, methanol) |
| Water | max. 5.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 223 °C |
GHS
相关法规
| RTECS# | RK0177586 |
运输信息
| HS编码* | 2938.90-000 |
应用
Asperosaponin VI: A Bioactive Saponin Found in the Medicinal Herb Dipsacus asper Wall
Asperosaponin VI is a kind of saponin found in the medicinal herb Dipsacus asper Wall, which has long been used as a traditional Chinese herbal medicine for the therapy of bone diseases such as osteoporosis.1) It has been reported that asperosaponin VI has many pharmacological effects, such as neuroprotective, cardioprotective, osteoprotective, anti-apoptosis.2-4) (The product is for research purpose only.)
References
- Traditional uses, processing methods, phytochemistry, pharmacology and quality control of Dipsacus asper Wall. ex C.B. Clarke: A review
- Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways
- Asperosaponin VI, A Saponin Component from Dipsacus asper Wall, induces Osteoblast Differentiation through Bone Morphogenetic Protein-2/p38 and Extracellular Signal-regulated Kinase 1/2 Pathway
- Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway
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