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CAS RN: 313-67-7 | 产品编码: A3599
产品编码 | A3599 |
纯度/分析方法 | >95.0%(T)(HPLC) |
分子式/分子量 | C__1__7H__1__1NO__7 = 341.28 |
外观与形状(20°C) | 固体 |
储存温度 | 冷藏 (0-10°C) |
储存在惰性气体下 | 存放于惰性气体之中 |
应避免的情况 | 空气,湿气 (吸湿),加热 |
包装和容器 | 100MG-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 313-67-7 |
Reaxys-RN | 345159 |
MDL编号 | MFCD00004996 |
技术规格
Appearance | White to Yellow powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Purity(Neutralization titration) | min. 95.0 % |
NMR | confirm to structure |
物性(参考值)
熔点 | 278 °C |
GHS
象形图 | |
信号词 | Danger |
危险性说明 | H301 : Toxic if swallowed. H350 : May cause cancer. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
RTECS# | CF3325000 |
运输信息
UN编号 | UN2811 |
类别 | 6.1 |
包装类别 | III |
HS编码* | 2932.99-000 |
应用
Aristolochic Acid: A Carcinogenic, Mutagenic, and Nephrotoxic Phytochemical
Aristolochic acid is a carcinogenic, mutagenic, and nephrotoxic phytochemical found in the flowering plant family Aristolochiaceae, which has been widely used as a traditional herbal medicine to treat kidney and urinary problems. In 1994, Vanherweghem et al. reported that a cause of progressive interstitial fibrosis of the kidney was associated with herbs containing aristolochic acid.1) Since then, aristolochic acid has been reported to be associated with the development of progressive interstitial fibrosis of the kidney, called aristolochic acid nephropathy (AAN), and with urothelial cancer in AAN patients.2-4) (The product is for research purpose only.)
References
- 1) Identification of aristolochic acid in Chinese herbs
- 2) Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)
- 3) Aristolochic acid and the etiology of endemic (Balkan) nephropathy
- 4) An integrated view of aristolochic acid nephropathy: update of the literature (a review)
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