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CAS RN: 1715-30-6 | 产品编码: A3389
Alexidine Dihydrochloride
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纯度/分析方法: >98.0%(HPLC)(N)
别名：
- 阿来西定二盐酸盐
- 1,1'-六亚甲基双[5-(2-乙基己基)双胍]二盐酸盐
- N,N''-双(2-乙基己基)-3,12-二亚氨基-2,4,11,13-四氮杂十四烷二酰亚胺二盐酸盐
- 1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide Dihydrochloride
- N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Dihydrochloride
产品文档：
| 产品编码 | A3389 |
| 纯度/分析方法 | >98.0%(HPLC)(N) |
| 分子式/分子量 | C__2__6H__5__6N__1__0·2HCl = 581.72 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (-20°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 湿气 (吸湿),加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 1715-30-6 |
| Reaxys-RN | 5698790 |
| PubChem物质ID | 468590270 |
| MDL编号 | MFCD00082369 |
技术规格
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 223.0 to 227.0 °C |
物性（参考值）
| 熔点 | 225 °C |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2925.29-000 |
应用
Alexidine Dihydrochloride: A Cationic Bis(Biguanide) Antimicrobial Agent
Alexidine dihydrochloride is a cationic bis(biguanide) antimicrobial agent. It has been reported that alexidine binds to lipopolysaccharide and lipoteichoic acid and prevents microbial cell activation.1,2) In addition, alexidine induces apoptosis in cancer cell line, and inhibits the protein tyrosine phosphatase mitochondrion-1 (PTPM1).3,4) (The product is for research purpose only.)
References
- 1) Alexidine and chlorhexidine bind to lipopolysaccharide and lipoteichoic acid and prevent cell activation by antibiotics
- 2) Alexidine dihydrochloride has broad-spectrum Activities against diverse fungal pathogens
- 3) Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent
- 4) Pharmacological Targeting of the Mitochondrial Phosphatase PTPMT1
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技术规格
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