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CAS RN: 796-42-9 | 产品编码: A3339
AS-8351
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技术规格
| Appearance | White to Orange to Green powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 266 °C |
| 最大吸收波长 | 367 nm (MeOH) |
GHS
相关法规
运输信息
| HS编码* | 2933.39-000 |
应用
AS-8351: An Iron Chelator Inhibiting the Activity of Histone Demethylase
AS-8351 is reported to be an iron chelator with anti-tumor activity,1,2) and a histone demethylase inhibitor targeting KDM5B (JARID1B).3) (The product is for research purpose only.)
References
- 1) The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone
- 2) The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation
- 3) Conversion of human fibroblasts into functional cardiomyocytes by small molecules
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