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CAS RN: 14028-44-5 | 产品编码: A2499
Amoxapine
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| 产品编码 | A2499 |
| 纯度/分析方法 | >97.0%(GC)(T) |
| 分子式/分子量 | C__1__7H__1__6ClN__3O = 313.79 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 14028-44-5 |
| PubChem物质ID | 181085854 |
| Merck Index (14) | 576 |
| MDL编号 | MFCD00069210 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 97.0 % |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 178.0 to 182.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 179 °C |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H302 : Harmful if swallowed. H370 : Causes damage to organs. H341 : Suspected of causing genetic defects. H413 : May cause long lasting harmful effects to aquatic life. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | HQ4025500 |
运输信息
| HS编码* | 2934.99-000 |
应用
Studies on the Neuropharmacology of Amoxapine
References
- Pharmacological profile of antidepressants and related compounds at human monoamine transporters
- Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline
- Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters
- Is amoxapine an atypical antipsychotic? Positron-emission tomography investigation of its dopamine2 and serotonin2 occupancy
- Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine
参考文献
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