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CAS RN: 464-92-6 | 产品编码: A2475
Asiatic Acid
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| 产品编码 | A2475 |
| 纯度/分析方法 | >97.0%(T) |
| 分子式/分子量 | C__3__0H__4__8O__5 = 488.71 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 464-92-6 |
| PubChem物质ID | 468590113 |
| MDL编号 | MFCD00238541 |
技术规格
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Specific rotation [a]20/D | +47.0 to +52.0 deg(C=0.1, MeOH) |
物性（参考值）
| 熔点 | 318 °C(dec.) |
| 比旋光度 [α]D | 50.3° (C=0.25,MeOH) |
GHS
| 危险性说明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相关法规
| RTECS# | YU9580000 |
运输信息
| HS编码* | 2918.19-000 |
应用
Asiatic Acid: A Pentacyclic Triterpene Possess Wide Pharmacological Activities
Asiatic acid is a pentacyclic triterpene extracted from Centella asiatica which is a tropical medicinal plant native to India, Sri Lanka, Madagascar, South Africa, Indonesia, and Malaysia. Asiatic acid possess wide pharmacological activities, and has been widely used in Indian traditional Ayurvedic medicine. In recent years, more and more studies have been reported about the pharmacological activities, clinical application and structure modification of asiatic acid. (The product is for research purpose only.)
References
- Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells
- Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells
- Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: Possible involvement of the IKK and MAPK pathways
- Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban (a review)
- Centella asiatica in food and beverage applications and its potential antioxidant and neuroprotective effect (a review)
- Determination of biologically active constituents in Centella asiatica
TCIMail
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