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CAS RN: 219773-47-4 | Product Number: E1224
Ecabet Sodium Hydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Sodium (4bS,8R,8aR)-8-Carboxy-2-isopropyl-4b,8-dimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-3-sulfonate Pentahydrate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Quantity |
Shipping Information
|
|---|---|---|---|---|---|---|
| 5G |
S$148.50
|
6 | 0 | Contact Us |
|
|
| 25G |
S$514.50
|
7 | 0 | Contact Us |
|
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* The storage conditions are subject to change without notice.
| Product Number | E1224 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__7NaO__5S·5H__2O = 492.56 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 219773-47-4 |
| PubChem Substance ID | 468591689 |
| MDL Number | MFCD28009632 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Neutralization titration) | min. 98.0 % |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | +58.0 to +62.0 deg(C=0.5, water) |
| Water | 17.0 to 19.0 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2916.39-000 |
Application
Ecabet Sodium: An Antiulcer and Gastroprotective Agent with Urease Inhibitory Activity
Ecabet sodium (TA-2711) is an antiulcer and gastroprotective agent. Many studies have indicated that ecabet sodium prevents the esophageal lesion by the inhibition of pepsin activity of gastric juice as well as the protection of the degradation of mucus, a defensive factor of mucosa. In addition, ecabet sodium shows bactericidal activity against H. pylori in acidic environments with inhibition of urease activity. (The product is for research purpose only.)
References
- Effects of the new antiulcer drug ecabet sodium (TA-2711) on pepsin activity. I. Inactivation of enzyme protein
- Effects of the new anti-ulcer drug ecabet sodium (TA-2711) on pepsin activity II. Interaction with substrate protein
- Ecabet sodium: a potential new agent in the management of distal colitis (a review)
- Ecabet sodium, a locally acting antiulcer drug, inhibits urease activity of Helicobacter pylori
- Chemistry and mechanism of urease inhibition (a review)
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