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CAS RN: 24729-96-2 | Product Number: C2257
Clindamycin Phosphate
Purity: >97.0%(T)
Synonyms:
- Clindamycin 2-Dihydrogen Phosphate
Product Documents:
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Product Number | C2257 |
Purity / Analysis Method | >97.0%(T) |
Molecular Formula / Molecular Weight | C__1__8H__3__4ClN__2O__8PS = 504.96 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 24729-96-2 |
Reaxys Registry Number | 463386 |
PubChem Substance ID | 87560447 |
Merck Index (14) | 2356 |
MDL Number | MFCD07793328 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(Nonaqueous Titration) | min. 97.0 %(calcd.on anh.substance) |
Specific rotation [a]20/D | +115.0 to +130.0 deg(C=1, H2O)(calcd.on anh.substance) |
Water | max. 6.0 % |
Properties (reference)
Melting Point | 114 °C |
Specific Rotation | 122° (C=1,H2O) |
Solubility in water | Soluble |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H302 : Harmful if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
RTECS# | GF2625000 |
Transport Information:
H.S.code* | 2941.90-000 |
Application
Clindamycin Phosphate: A Water Soluble Clindamycin
Clindamycin phosphate is a prodrug of lincosamide antibiotic clindamycin hydrochloride [C2256], and is designed as a highly water soluble form of the poorly water soluble parent compound clindamycin. Meanwhile, clindamycin phosphate has been used as a chiral selector.
References
- Parenteral development of clindamycin-2-phosphate (a review)
- K. W. Riebe, T. O. Oesterling, Bull. Parenteral Drug Assoc. 1972, 26, 139.
- Case Study: Clindamycin 2-Phosphate, A Prodrug of Clindamycin (a review)
- Investigation of enantiomeric separation of basic drugs by capillary electrophoresis using clindamycin phosphate as a novel chiral selector
- Evaluation of the enantioseparation capability of the novel chiral selector clindamycin phosphate towards basic drugs by micellar electrokinetic chromatography
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