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CAS RN: 51-83-2 | Product Number: C0596
Carbamylcholine Chloride
Purity: >98.0%(T)
Synonyms:
- Carbachol
- (2-Carbamoyloxyethyl)trimethylammonium Chloride
- Choline Chloride Carbamate
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Quantity |
---|---|---|---|---|
10G |
S$114.00
|
12 | 15 |
|
25G |
S$220.50
|
15 | ≥100 |
|
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to order TCI products.
* The storage conditions are subject to change without notice.
Product Number | C0596 |
Purity / Analysis Method | >98.0%(T) |
Molecular Formula / Molecular Weight | C__6H__1__5ClN__2O__2 = 182.65 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Hygroscopic |
CAS RN | 51-83-2 |
Reaxys Registry Number | 3917459 |
PubChem Substance ID | 87565693 |
SDBS (AIST Spectral DB) | 4583 |
Merck Index (14) | 1779 |
MDL Number | MFCD00012011 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(Nonaqueous Titration) | min. 98.0 % |
Solubility in Water | almost transparency |
Properties (reference)
Melting Point | 189 °C |
Solubility (slightly sol. in) | Alcohol |
Solubility (insoluble in) | Ether, Acetone, Chloroform |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H300 : Fatal if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | GA0875000 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | II |
H.S.code* | 2924.19-000 |
Application
Reagent for dysuria model
References
- TRK-380, a novel selective human β3-adrenoceptor agonist, ameliorates formalin-induced pollakiuria in rats and carbachol-induced bladder contraction in dogs
- Inhibitory effects of salviae miltiorrhizae radix (danshen) and puerariae lobatae radix (gegen) in carbachol-induced rat detrusor smooth muscle contractility
- W. Liang, I. W. Teong J. C. Koon, C. B. Lau, K. P. Fung, P. C. Leung, Int. J. Physiol. Pathophysiol. Pharmacol. 2012, 4, 36.
- Frusemide potentiates acetylcholine and carbachol in contracting the rat urinary bladder
- J. N. Okpukpara, P. A. Akah, J. Pharm. Pharmacol. 1990, 42, 597.
- Carbachol-induced sustained tonic contraction of rat detrusor muscle
- Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladder
- Inhibitory effects of various L-type and T-type calcium antagonists on electrically generated, potassium-induced and carbachol-induced contractions of porcine detrusor muscle
- Carbachol-induced rabbit bladder smooth muscle contraction: roles of protein kinase C and Rho kinase
- Variations in carbachol- and ATP-induced contractions of the rat detrusor: effects of gender, mucosa and contractile direction
- The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels
Application
Reagent for asthenopia model
References
- Nitric oxide relaxes bovine ciliary muscle contracted by carbachol through elevation of cyclic GMP
- Effects of nitric oxide donors and nitric oxide synthase substrates on ciliary muscle contracted by carbachol and endothelin for possible use in myopia prevention
- C. Beauregard, Q. Liu, G. C. Chiou, J. Ocul. Pharmacol. Ther. 2001, 17, 1.
- Effects of phorbol ester on carbachol-induced contraction in bovine ciliary muscle: possible involvement of protein kinase C
- Inhibitory effects of amlexanox on carbachol-induced contractions of rabbit ciliary muscle and guinea-pig taenia caecum
- N. Watanabe, Y. Tominaga, K. Mizutani, T. Ogawa, H. Tsunobuchi-Ushijima, Y. Gomi, J. Pharm. Pharmacol. 2000, 52, 1377.
Application
Reagent for gastropathy (gastric secretion) model
Reference
- Inhibition of gastric acid secretion by cholinergic stimulation of the lateral hypothalamic area
- J. A. Gontijo, C. R. Silva-Netto, M. R. Furtado, Braz. J. Med. Biol. Res. 1990, 23, 361.
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