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CAS RN: 1310544-60-5 | Product Number: B4478
N,N'-Bis(2-pyridylmethyl)-1,2-ethylenediamine Tetrahydrochloride Dihydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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| Product Number | B4478 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__8N__4·4HCl·2H__2O = 424.19 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1310544-60-5 |
| Related CAS RN | 18653-95-7&4608-34-8 |
| Reaxys Registry Number | 17253314 |
| PubChem Substance ID | 253660938 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Argentometric Titration) | min. 98.0 %(calcd.on anh.substance) |
| Melting point | 219.0 to 223.0 °C |
| Water | 7.0 to 10.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 221 °C |
| Solubility in water | Soluble |
GHS
| Pictogram |
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| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
A Potentially Useful Reagent for Metallic Chelation
N,N'-Bis(2-pyridylmethyl)-1,2-ethylenediamine tetrahydrochloride (abbrev.: Bispicen or H2pmen) is a potentially useful reagent for metallic chelation. Recently, it has been reported as an agent for chelation therapies. (The product is for research purpose only.)
References
- Multidentate coordination compounds. Chelating properties of aliphatic amines containing α-pyridyl residues and other aromatic ring systems as donor groups
- Mononuclear and binuclear oxo-bridged iron(III) complexes of N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine (bispicen)
- Chemistry of Re with N,N'-Bis(2-pyridylmethyl)ethylenediamine (H2pmen): Hydrolysis, Dehydrogenation, and Ternary Complexes
- Structural and spectroscopic characterization of N,N'-bis(2-pyridylmethyl)-ethylenediamine tetrahydrochloride dihydrate
- Two pyridine derivatives as potential Cu(II) and Zn(II) chelators in therapy for Alzheimer's disease
- Design and synthesis of 8-hydroxyquinoline-based radioprotective agents
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