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CAS RN: 568-73-0 | Product Number: T4153
Tanshinone I
Purity: >95.0%(HPLC)
Synonyms:
- Tanshinone A
- Tanshinquinone I
- 1,6-Dimethylphenanthro[1,2-b]furan-10,11-dione
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
250MG |
$172.00
|
29 | 0 | Contact Us |
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Product Number | T4153 |
Purity / Analysis Method | >95.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__8H__1__2O__3 = 276.29 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Hygroscopic,Heat Sensitive |
Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 568-73-0 |
Reaxys Registry Number | 237369 |
MDL Number | MFCD00210563 |
Specifications
Appearance | Red to Dark red powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Melting point | 230.0 to 234.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 231 °C |
GHS
Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
RTECS# | SF8282630 |
Transport Information:
H.S.code* | 2932.99-000 |
Application
Tanshinone I: A Major Lipophilic Component Extracts from the Root of Salvia miltiorrhiza
Tanshinone I, a derivative of phenanthrenequinone, is a major lipophilic component extracted from the root of Salvia miltiorrhiza, which is widely used in Chinese herbal medicine for the treatment of cardiovascular diseases. Biological studies suggested that tanshinone I shows a variety of pharmacological activities, such as anticancer, anti-inflammatory, amyloid-β anti-aggregation and cardio-cerebrovascular protective activities. (The product is for research purpose only.)
Reference
- Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
- Anticancer effects of tanshinone I in human non-small cell lung cancer
- Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses
- S. Y. Kim, T. C. Moon, H. W. Chang, K. H. Son, S. S. Kang, H. P. Kim, Phytother. Res. 2002, 16, 616.
- Research and development of natural product Tanshinone I: pharmacology, total synthesis, and structure modifications (a review)
- Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
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