Maximum quantity allowed is 999
Please select the quantity
CAS RN: 483-14-7 | Product Number: T3311
L-Tetrahydropalmatine
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
$108.00
|
9 | 1 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | T3311 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__5NO__4 = 355.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 483-14-7 |
| Reaxys Registry Number | 96288 |
| PubChem Substance ID | 253661327 |
| MDL Number | MFCD03265591 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 96.0 % |
| Melting point | 140.0 to 144.0 °C |
| Specific rotation [a]20/D | -278.0 to -298.0 deg(C=1, EtOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 142 °C |
| Specific Rotation | -283° (C=1,EtOH) |
| Maximum Absorption Wavelength | 280 nm |
GHS
Related Laws:
| RTECS# | HQ1792500 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
A Plant Alkaloid Effective in Multidrug Resistant Cancer Cells
L-Tetrahydropalmatine (L-THP or l-THP), the active enantiomer of THP [T3650], is an alkaloid found in several plant species such as Corydalis and Stephania. Corydalis Tuber (Corydalis yanhusuo) containing L-THP has been used for traditional Chinese pain medicine. Since L-THP antagonizes dopamine D1/D2 receptors and acts on dopamine D3 receptors, as well as α-adrenergic and serotonin receptors, it may have utility for treating opioid addiction.1,2) Furthermore, it has been reported that L-THP shows activity against antineoplastic resistant cancer cells.3) (The product is for research purpose only.)
References
- (－)-Tetrahydropalmatine and its analogues as new dopamine receptor antagonists
- l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction (a review)
- The two enantiomers of tetrahydropalmatine are inhibitors of P-gp, but not inhibitors of MRP1 or BCRP
PubMed Literature
Articles/Brochures
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.