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CAS RN: 89396-94-1 | Product Number: I0901
Imidapril Hydrochloride
Purity: >98.0%(T)(HPLC)
Synonyms:
- (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Acid Hydrochloride
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
25MG |
$155.00
|
11 | 1 |
100MG |
$463.00
|
16 | 2 |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
Product Number | I0901 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__2__7N__3O__6·HCl = 441.91 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Hygroscopic |
Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 89396-94-1 |
Related CAS RN | 89371-37-9 |
Reaxys Registry Number | 4835331 |
PubChem Substance ID | 253661853 |
Merck Index (14) | 4911 |
MDL Number | MFCD00923828 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Specific rotation [a]20/D | -65.0 to -69.0 deg(C=1, MeOH) |
Properties (reference)
Melting Point | 206 °C(dec.) |
Specific Rotation | -67° (C=1,MeOH) |
Solubility in water | Soluble |
Solubility (slightly sol. in) | Ethanol |
Solubility (insoluble in) | Ether |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
RTECS# | NI8927400 |
Transport Information:
H.S.code* | 2933.29-000 |
Application
Imidapril Hydrochloride: A Non-Sulfhydryl Group and Long-Acting ACE Inhibitor
Imidapril hydrochloride is an ethyl ester prodrug of the active metabolite imidaprilat. Imidapril is a long-acting and non-sulfhydryl group drug with fewer side effects angiotensin-converting enzyme (ACE) inhibitor to suppress the conversion of angiotensin I to angiotensin II and thereby reduce total peripheral resistance (TRP) and systemic blood pressure (BP). (The product is for research purpose only.)
References
- Protection of the cardiovascular system by imidapril, a versatile angiotensin-converting enzyme inhibitor (a review)
- Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin-converting enzyme inhibitors. An update (a review)
- Imidapril: a review of its use in essential hypertension, type 1 diabetic nephropathy and chronic heart failure
- Imidapril: will fewer adverse events translate into better long-term outcomes? (a review)
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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