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CAS RN: 603-50-9 | Product Number: B5066
Bisacodyl
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 4,4'-(2-Pyridylmethylene)bisphenol Diacetate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 5G |
$52.00
|
≥40 | 5 |
| 25G |
$169.00
|
16 | 3 |
* Please contact our distributors or
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | B5066 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__1__9NO__4 = 361.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 603-50-9 |
| Reaxys Registry Number | 323727 |
| PubChem Substance ID | 354334116 |
| Merck Index (14) | 1242 |
| MDL Number | MFCD00038039 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 132.0 to 136.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 134 °C |
| Maximum Absorption Wavelength | 220(MeOH) nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | SM8750000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Bisacodyl: A Diphenylmethane Stimulant Laxative
Bisacodyl is used as a diphenylmethane stimulant laxative. Bisacodyl is hydrolyzed by intestinal brush border enzymes and colonic bacteria to form an active metabolite bis(p-hydroxyphenyl)-2-pyridylmethane that acts directly on the colonic mucosa to produce colonic peristalsis. (The product is for research purpose only.)
References
- Entacetylierung und Resorption von phenolischen Laxantien
- Bis-(p-hydroxyphenyl)-pyridyl-2-methane: The common laxative principle of Bisacodyl and sodium picosulfate.
- Aspects of the pharmacology of diphenylmethane laxatives (bisacodyl, oxyphenisatin and phenolphthalein derivatives) (a review)
- R. B. Sund, Norvegica Pharm. Acta 1983, 45, 125.
- Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase
- High-performance liquid chromatographic determination of bisacodyl in pharmaceutical dosage forms marketed in Australia
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