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CAS RN: 326914-06-1 | Product Number: M3107
MHY 1485
Purity: >95.0%(HPLC)
Synonyms:
- 4,6-Di(4-morpholinyl)-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
- 4,6-Dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
Product Documents:
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Product Number | M3107 |
Purity / Analysis Method | >95.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__7H__2__1N__7O__4 = 387.40 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 326914-06-1 |
Reaxys Registry Number | 9952068 |
PubChem Substance ID | 354335544 |
MDL Number | MFCD00489974 |
Specifications
Appearance | White to Amber powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Properties (reference)
Melting Point | 259 °C |
GHS
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Transport Information:
H.S.code* | 2934.99-000 |
Application
細胞透過性mTOR活性化剤,MHY1485
MHY1485 is a cell-permeable activator of mTOR (mammalian target of rapamycin) which a serine/threonine protein kinase that controls critical cellular processes such as growth, proliferation, and protein synthesis. MHY1485 has been shown to inhibit autophagy. For your reference, the best-known inhibitor of mTOR is rapamycin [R0097].
References
- Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion
- MHY1485 activates mTOR and protects osteoblasts from dexamethasone
PubMed Literature
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