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CAS RN: 71675-85-9 | Product Number: A2450
Amisulpride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
$87.00
|
4 | 0 | It can be shipped in about 2 weeks after ordering | |
| 1G |
$392.00
|
3 | 36 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | A2450 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__7N__3O__4S = 369.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 71675-85-9 |
| Reaxys Registry Number | 6876191 |
| PubChem Substance ID | 135727298 |
| Merck Index (14) | 485 |
| MDL Number | MFCD00866691 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 125.0 to 129.0 °C |
Properties (reference)
| Melting Point | 127 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | CV2308701 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Amisulpride: A Selective Dopamine D2/D3 Receptors Antagonist
Amisulpride, a substituted benzamide derivative, is a selective dopamine D2/D3 receptors antagonist. Amisulpride binds selectively to dopaminergic D2 and D3 receptor subtypes without any affinity for D1, D4 and D5 receptor subtypes, in limbic system. Amisulpride is devoid of affinity for serotonin receptors or other neurogenic receptors such as histamine, cholinergic and adrenergic receptors. Recently, the amisulpride antagonism of 5-HT7 receptors has been reported. (The product is for research purpose only.)
References
- Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
- Psychopharmacological profile of amisulpride: an antipsychotic drug with presynaptic D2/D3 dopamine receptor antagonist activity and limbic selectivity
- Amisulpride: limbic specificity and the mechanism of antipsychotic atypicality (a review)
- Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo
- Stereospecific determination of amisulpride, a new benzamide derivative, in human plasma and urine by automated solid-phase extraction and liquid chromatography on a chiral column. Application to pharmacokinetics
- Comparative validation of amisulpride determination in pharmaceuticals by several chromatographic, electrophoretic and spectrophotometric methods
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