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CAS RN: 27724-96-5 | Product Number: C3454
Cetraxate Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-[4-[[trans-4-(Aminomethyl)cyclohexyl]carbonyloxy]phenyl]propanoic Acid Hydrochloride
Product Documents:
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| 250MG |
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| Product Number | C3454 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__3NO__4·HCl = 341.83 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 27724-96-5 |
| Related CAS RN | 34675-84-8 |
| Reaxys Registry Number | 5681006 |
| PubChem Substance ID | 354334777 |
| Merck Index (14) | 2024 |
| MDL Number | MFCD01722166 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 240 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2922.49-000 |
Application
Cetraxate Hydrochloride: A Gastrointestinal Agent with a Cytoprotective Effect
Cetraxate hydrochloride is a gastrointestinal agent which has a cytoprotective effect. It is reported that cetraxate increased gastric mucosal blood flow and inhibited the ulcerogenic action of acetylsalicylic acid [A2262], phenylbutazone [P1686], indomethacin [I0655], et al. (The product is for research purpose only.)
References
- Anti-ulcer effects of 4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride (cetraxate) on various experimental gastric ulcers in rats
- Studies on the mechanism of action of cetraxate [4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride], a new anti-ulcer agent
- Cytoprotective action of cetraxate against hydrochloric acid·ethanol-induced gastric lesion in rats
- Influence of Helicobacter pylori infection and cetraxate on gastric mucosal blood flow during healing of endoscopic mucosal resection-induced ulcers
Application
Cetraxate Hydrochloride: An Antiulcer and Anti-Gastritis Agent
Cetraxate hydrochloride is an antiulcer and anti-gastritis agent which has a cytoprotective effect. It produces a dose-related increase in mucosal blood flow. In addition, it is reported that cetraxate is effective for the eradication of Helicobacter pylori infection. (The product is for research purpose only.)
References
- Anti-ulcer effects of 4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride (cetraxate) on various experimental gastric ulcers in rats
- Oxyradical generation from leukocytes during endotoxin-induced microcirculatory disturbance in rat mesentery. Attenuating effect of cetraxate
- Cetraxate, a mucosal protective agent, combined with omeprazole, amoxycillin, and clarithromycin increases the eradication rate of Helicobacter pylori in smokers
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