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CAS RN: 143527-70-2 | Product Number: B4127
(4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic Acid
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Purity: >98.0%(GC)(T)
Synonyms:
- (4S,5R)-3-Boc-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
$84.00
|
7 | ≥40 | Contact Us |
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| Product Number | B4127 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__7H__2__3NO__5 = 321.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 143527-70-2 |
| Reaxys Registry Number | 5827317 |
| PubChem Substance ID | 354334489 |
| MDL Number | MFCD09263630 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 112.0 to 116.0 °C |
| Specific rotation [a]20/D | -1.5 to -3.5 deg(C=1, CHCL3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 114 °C |
| Specific Rotation | -2° (C=1,CHCl3) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2934.99-000 |
Application
A Synthetic Intermediate of the Side Chains of Docetaxel and Paclitaxel
This product is used for the synthesis of the docetaxel (taxotere) [D4102] and paclitaxel (taxol) [P1632] side chains.
References
- Improved protection and esterification of a precursor of the Taxotere and taxol side chains
- Synthesis of Taxol and Taxotere side chains by 2-(trimethylsilyl)thiazole based homologation of L-phenylglycine
- Design and Synthesis of a Taxoid Library Using Radiofrequency Encoded Combinatorial Chemistry
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