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CAS RN: 163622-50-2 | Product Number: I1161
5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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![5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine")
Purity: >95.0%(T)(HPLC)
Synonyms:
- 4-Amino-5-iodopyrrolo[2,3-d]pyrimidine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$81.00
|
≥40 | 0 | It can be shipped in about 4-5 weeks after ordering | |
| 5G |
$237.00
|
0 | 0 | It can be shipped in about 4-5 weeks after ordering |
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* The storage conditions are subject to change without notice.
| Product Number | I1161 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__6H__5IN__4 = 260.04 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 163622-50-2 |
| Reaxys Registry Number | 27008569 |
| MDL Number | MFCD13619882 |
Specifications
| Appearance | White to Brown powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.59-000 |
Application
A Synthetic Intermediate of Pyrrolo[2,3-d]pyrimidin-Based Derivative Kinase Inhibitors
This product has been used as a synthetic intermediate of pyrrolo[2,3-d]pyrimidin-based derivative kinase inhibitors,1-4) including nucleoside analogs4) such as 5-Iodotubercidin [I1156].
References
- 1) Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii
- 2) Identification of 5-(2,3-Dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as a new class of receptor-interacting protein kinase 1 (RIPK1) inhibitors, which showed potent activity in a tumor metastasis model
- 3) Identification of Pyrrolo[2,3-d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia
- 4) Bromo-deaza-SAH: A potent and selective DOT1L inhibitor
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