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Published TCIMAIL newest issue No.197 | Notice of Discontinuing the Use of Password-Protected Compressed Files | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
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CAS RN: 1143-70-0 | Product Number: U0154
Urolithin A
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 3,8-Dihydroxy-6H-benzo[c]chromen-6-one
- 3,8-Dihydroxyurolithin
- 3,8-Hydroxydibenzo-α-pyrone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
$119.00
|
6 | 5 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | U0154 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__8O__4 = 228.20 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1143-70-0 |
| Reaxys Registry Number | 206848 |
| MDL Number | MFCD20275235 |
Specifications
| Appearance | White to Yellow to Yellow green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | HP8752500 |
Transport Information:
| H.S.code* | 2932.20-000 |
Application
Urolithin A: A Secondary Metabolite with Antioxicant, Anti-Inflammatory and Antiproliferative Properties
Urolithin A is a secondary metabolite produced by gut bacteria from ingested ellagic acid [E0375] and ellagitannins which are polyphenols found in numerous fruits and vegetables.1) There are reports that urolithin A shows antioxicant, anti-inflammatory and antiproliferative properties.2,3) Furthermore, urolithin A induces mitophagy both in vitro and in vivo following oral consumption.3,4) (For reference, mitophagy is an evolutionarily conserved cellular process to remove dysfunctional or superfluous mitochondria.) (The product is for research purpose only.)
References
- 1) Ellagitannins, ellagic acid and their derived metabolites: A review about source, metabolism, functions and health (a revew)
- 2) Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism
- 3) Impact of the Natural Compound Urolithin A on Health, Disease, and Aging (a review)
- 4) Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
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