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CAS RN: 73590-85-9 | Product Number: O0437
Omeprazole Sulfide
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
$49.00
|
5 | 17 | It can be shipped in about 2 weeks after ordering | |
| 1G |
$173.00
|
10 | 35 | It can be shipped in about 2 weeks after ordering |
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| Product Number | O0437 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__9N__3O__2S = 329.42 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 73590-85-9 |
| Reaxys Registry Number | 6527371 |
| PubChem Substance ID | 253662400 |
| MDL Number | MFCD00869021 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 122.0 to 126.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 124 °C |
| Maximum Absorption Wavelength | 307(MeOH) nm |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
オメプラゾール の合成中間体かつ代謝生成物，オメプラゾールスルフィド
Omeprazole sulfide is a synthetic intermediate and a metabolite of omeprazole [O0359]. In 2000s, asymmetric oxidation of omeprazole sulfide to esomeprazole, the active (S)-enantiomer of omeprazole, has been reported.
References
- Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide
- A simple and sensitive bioanalytical assay for simultaneous determination of omeprazole and its three major metabolites in human blood plasma using RP-HPLC after a simple liquid-liquid extraction procedure
- Asymmetric synthesis of esomeprazole
- Catalytic asymmetric oxidation of heteroaromatic sulfides with tert-butyl hydroperoxide catalyzed by a titanium complex with a new chiral 1,2-diphenylethane-1,2-diol ligand
- Tetra(tetraalkylammonium)octamolybdate catalysts for selective oxidation of sulfides to sulfoxides with hydrogen peroxide
- Asymmetric Oxidation Catalysis by a Porphyrin-Inspired Manganese Complex: Highly Enantioselective Sulfoxidation with a Wide Substrate Scope
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