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CAS RN: 34562-97-5 | Product Number: N0998
Picamilon
Purity: >98.0%(T)(HPLC)
Synonyms:
- N-Nicotinoyl-GABA
- N-(3-Carboxypropyl)nicotinamide
- 4-(Nicotinamido)butyric Acid
- N-Nicotinoyl-γ-aminobutyric Acid
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
5G |
$116.00
|
16 | 5 | Contact Us |
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Product Number | N0998 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__0H__1__2N__2O__3 = 208.22 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 34562-97-5 |
Reaxys Registry Number | 398732 |
PubChem Substance ID | 253662452 |
MDL Number | MFCD00186518 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 211.0 to 215.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 213 °C |
GHS
Related Laws:
Transport Information:
H.S.code* | 2933.39-000 |
Application
GABAのプロドラッグ,ピカミロン
N-Nicotinoyl-γ-aminobutyric acid (picamilon), a prodrug of GABA [A0282], is able to cross the blood–brain barrier and then is hydrolyzed into GABA and nicotinic acid (niacin) [N0082].
References
- Evaluation of isonicotinoyl-γ-aminobutyric acid (GABA) and nicotinoyl-GABA as pro-drugs of GABA
- Research on the pharmacochemistry of some GABA and valproic acid derivatives
- Synthesis and evaluation of nicotinoylamino acid compounds as radiosensitizer
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