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CAS RN: 77671-31-9 | Product Number: E1370
Enoximone

Purity: >95.0%(HPLC)
Synonyms:
- 4-Methyl-5-[4-(methylthio)benzoyl]-1,3-dihydro-2H-imidazol-2-one
Product Documents:
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Product Number | E1370 |
Purity / Analysis Method | >95.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__2H__1__2N__2O__2S = 248.30 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive |
CAS RN | 77671-31-9 |
Reaxys Registry Number | 5036229 |
PubChem Substance ID | 468591738 |
MDL Number | MFCD00867130 |
Specifications
Appearance | Light yellow to Brown powder to crystal |
Purity(HPLC) | min. 95.0 area% |
NMR | confirm to structure |
Properties (reference)
Melting Point | 270 °C |
GHS
Related Laws:
RTECS# | NI8026700 |
Transport Information:
H.S.code* | 2933.29-000 |
Application
Enoximone: A Selective Inhibitor of the Phosphodiesterase-III (PDE-III)
Enoximone (MDL 17043), an imidazolone derivative, is a selective inhibitor of the phosphodiesterase-III enzyme (PDE-III) and possesses positive inotropic and vasodilatory properties, and is active by both oral and intravenous routes of administration.
References
- Characterization of the cardiovascular activities of a new cardiotonic agent, MDL 17043 (1,3-dihydro-4-methyl-5-[4-(methylthio)-benzoyl]-2H-imidazol-2-one)
- Biotransformation and pharmacokinetic overview of enoximone and its sulfoxide metabolite (a review)
- Enoximone. A review of its pharmacological properties and therapeutic potential
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