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CAS RN: 24169-02-6 | 제품번호: E0957
Econazole Nitrate
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•본 제품의 재고는 일본 본사의 재고입니다. 주문시, 5일안에 실험실까지 도착됩니다.
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•보관 조건은 예고없이 변경 될 수 있습니다. 제품 보관 조건의 최신 자료는 홈페이지에 기재되어 있으니 양해 부탁드립니다.
•본건의 원가격은 한국 대리점의 예상 판매가격입니다.자세한 정보가 필요하시면 연락해 주십시오.( SEJIN CI Co., Ltd. (한국총대리점) 전화 : 02-2655-2480 이메일 : sales@sejinci.co.kr)
•보관 조건은 예고없이 변경 될 수 있습니다. 제품 보관 조건의 최신 자료는 홈페이지에 기재되어 있으니 양해 부탁드립니다.
| 제품번호 | E0957 |
| Purity/Analysis Method | >98.0%(T)(HPLC) |
| M.F. / M.W. | C__1__8H__1__5Cl__3N__2O·HNO__3 = 444.69 |
| 물리적 상태 (20 ℃) | Solid |
| 보관 조건 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 24169-02-6 |
| 관련 CAS RN | 27220-47-9 |
| Reaxys-RN | 4836249 |
| PubChem Substance ID | 253660301 |
| Merck Index (14) | 3502 |
| MDL 번호 | MFCD00058160 |
규격표
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
물성치(참고치)
| mp | 161 °C(dec.) |
| Solubility in water | Insoluble |
| 용해성 (미세 용접) | Ethanol |
| 용해도 (불용성) | Ether |
GHS
| 픽토그램 |
|
| 신호 워드 | Warning |
| 위험물 및 유해 등록 | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 주의 사항 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
법규 정보
| RTECS # | NI4450000 |
운송 정보
| HS 번호* | 2933.29-000 |
Application
Econazole Nitrate: An Imidazole Antifungal Reagent with other Activities.
Econazole nitrate is an imidazole antifungal reagent which is very closely related structurally to another imidazole derivative, miconazole nitrate [M1769]. It has broad-spectrum antimycotic activity. In addition, it is reported as a blocker of Ca2+ influx, and an inhibitor of steroid aromatization. Recently, various drug delivery systems have been reported to enhance the drug antifungal activity.
References
- Econazole: a review of its antifungal activity and therapeutic efficacy
- Econazole Nitrate (description, synthesis, physical properties, stability and degradation products)
- Inhibition of calcium transport pathways in thymic lymphocyte by econazole, miconazole, and SKF 96365
- Imidazole antimycotics: selective inhibitors of steroid aromatization and progesterone hydroxylation
- Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation
PubMed Literature
기사 / 브로셔
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