Deuterated solvents are used in NMR analysis, where regular hydrogen (1H) is replaced with deuterium (2H). This substitution prevents the solvent from interfering with the NMR spectrum, making sample analysis easier. Additionally, deuterated solvents are used as a lock signal in NMR instruments, ensuring stable measurements.
References
1) NMR Chemical Shifts of Common Laboratory Solvents as Trace Impurities
3) Solvent Effects in NMR Spectroscopy. I. Chemical Shifts Induced by the Addition of Protic Substances to Benzene Solutions of Several Polar Compounds