Maximum quantity allowed is 999
Please select the quantity
CAS RN: 133550-30-8 | Product Number: T2962
Tyrphostin AG 490
Purity: >98.0%(T)(HPLC)
Synonyms:
- (E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
20MG |
₩96,200
|
9 | 0 | Contact Us | |
1G |
₩1,576,200
|
2 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | T2962 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__7H__1__4N__2O__3 = 294.31 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
CAS RN | 133550-30-8 |
Reaxys Registry Number | 4323263 |
PubChem Substance ID | 253661829 |
MDL Number | MFCD00236452 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 215 °C |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | UC6316197 |
Transport Information:
UN Number | UN3439 |
Class | 6.1 |
Packing Group | III |
H.S.code* | 2926.90-000 |
Application
JAK Inhibitor
References
- 1)The Janus kinases (Jaks)
- 2)Janus kinases: Components of multiple signaling pathways
- 3)Tyrphostines. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases
- 4)Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
- 5)JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response
- 6)Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b of signal transduction and cellular proliferation of antigen-activated human T cells
- 7)JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells
PubMed Literature
Articles/Brochures
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.