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CAS RN: 32004-67-4 | Product Number: S0906
Sulindac Sulfide
Purity: >98.0%(HPLC)
Synonyms:
- 5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic Acid
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
25MG |
₩353,400
|
5 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | S0906 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__1__7FO__2S = 340.41 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (-20°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 32004-67-4 |
Reaxys Registry Number | 2767481 |
MDL Number | MFCD00869764 |
Specifications
Appearance | Light yellow to Brown powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Melting point | 184.0 to 188.0 °C |
Properties (reference)
Melting Point | 186 °C |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. H317 : May cause an allergic skin reaction. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | NK8236000 |
Transport Information:
H.S.code* | 2930.90-900 |
Application
A Cyclooxygenases (COX) Inhibitor, Sulindac Sulfide
Sulindac sulfide, an active metabolite of sulindac sulfoxide (sulindac) [U0099], is a cyclooxygenases (COX) inhibitor. In recent years, there has been growing interest in Sulindac sulfide and other non-steroidal anti-inflammatory drugs (NSAID) because of their anti-tumor activity. Studies with sulindac sulfide have been indicated that it may also function as an anti-tumor agent by stimulating apoptosis. (The product is for research purpose only.)
References
- A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
- Effects of sulindac and oltipraz on the tumorigenicity of 4-(methylnitrosamino)1-(3-pyridyl)-1-butanone in A/J mouse lung
- Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells
- Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis
- Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma
Articles/Brochures
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