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CAS RN: 138844-81-2 | Product Number: S0877
Sodium Ibandronate
Purity: >90.0%(T)
Synonyms:
- Ibandronic Acid Sodium Salt
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | S0877 |
Purity / Analysis Method | >90.0%(T) |
Molecular Formula / Molecular Weight | C__9H__2__2NNaO__7P__2 = 341.21 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 138844-81-2 |
Related CAS RN | 114084-78-5 |
Reaxys Registry Number | 14511791 |
PubChem Substance ID | 160871235 |
Merck Index (14) | 4873 |
MDL Number | MFCD07197214 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(Neutralization titration) | min. 90.0 % |
Drying loss | max. 10.0 % |
Properties (reference)
Solubility in water | Soluble |
GHS
Related Laws:
RTECS# | SZ8563300 |
Transport Information:
H.S.code* | 2931.49-900 |
Application
Studies of the Inhibition of Bone Resorption
References
- Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
- Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
- J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers, J. Pharmacol. Exp. Ther. 2001, 296, 235.
- Bisphosphonates act on rat bone resorption through the mediation of osteoblasts
- Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
Application
Bone Resorption Inhibitors
References
- 1)Anti-bone resorption
- a)J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers., J. Pharmacol. Exp. Ther. 2001, 296, 235.
- b)E. Hiroi-Furuya, T. Kameda, K. Hiura, H. Mano, K. Miyazawa, Y. Nakamaru, M. Watanabe-Mano, N. Okuda, J. Shimada, Y. Yamamoto, Y. Hakeda, M. Kumegawa, Calcif. Tissue Int. 1999, 64, 219.
- 2)In vitro anti-tumor effects and its in vivo role
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