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CAS RN: 128-20-1 | Product Number: P3084
5β-Pregnan-3α-ol-20-one
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Purity: >95.0%(HPLC)
Synonyms:
- Pregnanolone
- 3α-Hydroxy-5β-pregnan-20-one
- 1-[(3R,5R,8R,9S,10S,13S,14S,17S)-3-Hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethan-1-one
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
₩168,400
|
18 | 31 | Contact Us | |
| 25MG |
₩521,700
|
19 | 25 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | P3084 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__3__4O__2 = 318.50 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 128-20-1 |
| Reaxys Registry Number | 3211364 |
| MDL Number | MFCD00067137 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 149.0 to 153.0 °C |
| Specific rotation | +106 to +116 deg(C=1, ethanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 151 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | TU4384000 |
Transport Information:
| H.S.code* | 2937.29-000 |
Application
5β-Pregnan-3α-ol-20-one: An Endogenous Neuroactive Steroid
5β-Pregnan-3α-ol-20-one (or pregnanolone) and its stereoisomer, 3β-hydroxy-5α-pregnan-20-one [H1839], are metabolites of the ovarian/adrenal steroid progesterone [P0478].1) These metabolites are endogenous neuroactive steroids that act as a positive allosteric modulator (PAM) of γ-aminobutyric acid A (GABAA) receptors with anesthetic, anxiolytic, and anti-convulsant effects.2,3) (The product is for research purpose only.)
References
- 1) Neurosteroids: Biosynthesis and Function of These Novel Neuromodulators
- 2) Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives (a review)
- 3) Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors
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