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CAS RN: 74150-27-9 | Product Number: P2779
Pimobendan
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 6-[2-(4-Methoxyphenyl)-1H-benzo[d]imidazol-6-yl]-5-methyl-4,5-dihydropyridazin-3(2H)-one
- 6-[2-(4-Methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
₩196,100
|
0 | 14 | Contact Us | |
| 250MG |
₩584,600
|
20 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | P2779 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__1__8N__4O__2 = 334.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 74150-27-9 |
| Reaxys Registry Number | 4207330 |
| PubChem Substance ID | 468592720 |
| MDL Number | MFCD00761648 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 249 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | UR6373000 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
A Benzimidazole-Pyridazinone Derivative with Phosphodiesterase (Type III) Inhibition and Calcium-Sensitizing Properties
Pimobendan, a benzimidazole-pyridazinone derivative, is used as a veterinary cardiotonic vasodilator. It has been reported that pimobendan exerts its stimulatory myocardial effect by a dual mechanism of action: increase in calcium sensitivity of cardiac myofilaments and inhibition of phosphodiesterase (Type III). (The product is for research purpose only.)
References
- Cardiovascular profile of pimobendan, a benzimidazole-pyridazinone derivative with vasodilating and inotropic properties
- Calcium sensitization with pimobendan: pharmacology, haemodynamic improvement, and sudden death in patients with chronic congestive heart failure (a review)
- Mechanisms of action of calcium-sensitizing drugs (a review)
- Mechanism of action of Ca2+ sensitizers - Update 2001
Product Documents (Note: Some products will not have analytical charts available.)
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