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CAS RN: 88150-62-3 | Product Number: P2406
Phthaloyl Amlodipine
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
- 3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-(1,3-dioxoisoindolin-2-yl)ethoxy]methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩50,000
|
3 | 2 | It can be shipped in about 2 weeks after ordering | |
| 5G |
₩168,400
|
14 | 5 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | P2406 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__8H__2__7ClN__2O__7 = 538.98 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 88150-62-3 |
| Reaxys Registry Number | 6026908 |
| PubChem Substance ID | 468592595 |
| MDL Number | MFCD07782096 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 150.0 to 154.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 152 °C |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
An Impure Substance in the Synthesis of Amlodipine Besylate
This product has been reported as an impure substance in the synthesis of amlodipine besylate [A2353] which is a long-acting dihydropyridine-type calcium channel antagonist or blocker (CCB) used for the treatment of hypertension and cardiovascular disease.
References
- Long-acting dihydropyridine calcium antagonists. 1. 2-Alkoxymethyl derivatives incorporating basic substituents
- Sources of impurities - investigation of 4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-[(2-phthalimidoethoxy)methyl]-1,4-dihydropyridine traces formation during the synthesis of amlodipine besylate
- Identification and characterization of potential impurities of amlodipine maleate
- Enantiomeric separation of amlodipine and its two chiral impurities by nano-liquid chromatography and capillary electrochromatography using a chiral stationary phase based on cellulose tris(4-chloro-3-methylphenylcarbamate)
Product Documents (Note: Some products will not have analytical charts available.)
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