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CAS RN: 212631-79-3 | Product Number: P2174
PD 184352
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Purity: >98.0%(HPLC)
Synonyms:
- 2-(2-Chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
₩445,900
|
7 | 1 | Contact Us | |
| 100MG |
₩1,320,900
|
10 | 2 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | P2174 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__4ClF__2IN__2O__2 = 478.66 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 212631-79-3 |
| Reaxys Registry Number | 10032343 |
| PubChem Substance ID | 468592581 |
| MDL Number | MFCD02683961 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 5.30 to 6.30 % |
| Melting point | 176.0 to 180.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 178 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2928.00-000 |
Application
PD184352: A Selective Inhibitor of Mitogen-Activated Protein Kinase (MAPK)
PD184352 (or Cl-1040) is an orally active and selective inhibitor of mitogen-activated protein kinase (MAPK or MAP kinase), a type of serine/threonine protein kinase.
References
- Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
- Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia
- CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK) (a review)
- The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (Cl-1040) selectively induces apoptosis in malignant schwannoma cell lines
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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